MersV1, Main, Exploration, bibRecord, 000404

Remote Laboratory Management: Respiratory Virus Diagnostics.

Identifieur interne : 000404 ( Main/Exploration ); précédent : 000403; suivant : 000405

Remote Laboratory Management: Respiratory Virus Diagnostics.

Auteurs : Elena V. Petrova [États-Unis] ; Vasanthi Avadhanula [États-Unis] ; Sarah Michel [États-Unis] ; Karen E. Gincoo [États-Unis] ; Pedro A. Piedra [États-Unis] ; Sharmila Anandasabapathy [États-Unis]

Source :

Journal of visualized experiments : JoVE [ 1940-087X ] ; 2019.

RBID : pubmed:31009009

Descripteurs français

KwdFr :
- Grippe humaine (diagnostic), Humains, Laboratoires, Orthomyxoviridae (génétique), Réaction de polymérisation en chaine en temps réel.
MESH :
- diagnostic : Grippe humaine.
- génétique : Orthomyxoviridae.
- Humains, Laboratoires, Réaction de polymérisation en chaine en temps réel.

English descriptors

KwdEn :
- Humans, Influenza, Human (diagnosis), Laboratories, Orthomyxoviridae (genetics), Real-Time Polymerase Chain Reaction.
MESH :
- diagnosis : Influenza, Human.
- genetics : Orthomyxoviridae.
- Humans, Laboratories, Real-Time Polymerase Chain Reaction.

Abstract

An uptick in recent pandemics (Ebola, Zika, MERS, influenza, etc.) underlines the need for a more 'nimble,' coordinated response that addresses a multitude of issues ranging from transportation, access, facilities, equipment, and communication to provider training. To address this need, we have developed an innovative, scalable, logistics-enhanced, mobile, laboratory facility for emergencies and epidemics in resource-constrained global settings. Utilizing a background in clinical operations as an academic medical center, we designed a rapidly-deployable, modular BSL-2 and BSL-3 facility with user-friendly software for tracking and management of drugs and supplies in remote regions during epidemics and outbreaks. Here, we present our intermodal, mobile, expandable shipping-container laboratory units. The design of the laboratory facilitates off-grid usage by minimizing power consumption and allowing alternate water sources. The unit's information communication technology (ICT) platform provides (i) user-friendly tablet-based documentation, (ii) enhanced tracking of patients and supplies, and (iii) integrated communication onsite with built-in telehealth capabilities. To ensure quality in remote environments, we have developed a checklist for a basic laboratory workflow and a protocol for respiratory viral diagnosis using reverse-transcription polymerase chain reaction (RT-PCR). As described, this innovative and comprehensive approach allows for the provision of laboratory capability in resource-limited global environments.

DOI: 10.3791/59188
PubMed: 31009009

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en">An uptick in recent pandemics (Ebola, Zika, MERS, influenza, etc.) underlines the need for a more 'nimble,' coordinated response that addresses a multitude of issues ranging from transportation, access, facilities, equipment, and communication to provider training. To address this need, we have developed an innovative, scalable, logistics-enhanced, mobile, laboratory facility for emergencies and epidemics in resource-constrained global settings. Utilizing a background in clinical operations as an academic medical center, we designed a rapidly-deployable, modular BSL-2 and BSL-3 facility with user-friendly software for tracking and management of drugs and supplies in remote regions during epidemics and outbreaks. Here, we present our intermodal, mobile, expandable shipping-container laboratory units. The design of the laboratory facilitates off-grid usage by minimizing power consumption and allowing alternate water sources. The unit's information communication technology (ICT) platform provides (i) user-friendly tablet-based documentation, (ii) enhanced tracking of patients and supplies, and (iii) integrated communication onsite with built-in telehealth capabilities. To ensure quality in remote environments, we have developed a checklist for a basic laboratory workflow and a protocol for respiratory viral diagnosis using reverse-transcription polymerase chain reaction (RT-PCR). As described, this innovative and comprehensive approach allows for the provision of laboratory capability in resource-limited global environments.</div>
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Serveur d'exploration MERS

Remote Laboratory Management: Respiratory Virus Diagnostics.

Remote Laboratory Management: Respiratory Virus Diagnostics.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration MERS
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